Cracks in 100% nearly all topic of importance to you, like. A valuable biotechnological approach to the melanin-mediated synthesis of silver nanostructures with broad-spectrum antimicrobial activity has been developed. Melanin: What Makes Black People Black. WebGREAT BOOK OF MELANIN RESEARCH PUBLIC OFFICIAL BONDS BOOK (POB) Public Official Bonds - Make Them Pay!!! There are 5 things that the Pineal gland is responsible for: Inner Eye Cracks in 100% nearly all topic of importance to you, like. Print length 103 pages Language English Publisher Lushena Books Publication date Very likely, melanin photoprotection is also due to its ability to quench excited states of certain molecules and scavenge ROS that may be generated in pigmented cells [126]. In a similar study, [56] noted that the production of pigment by Monascus species also was favored when the fungus was grown in the dark. Introductory Chapter: Melanin, a Versatile Guardia Department of Biochemistry and Technology Chemistry, Institute of Chemistry, UNESP, So Paulo State University, Araraquara, So Paulo, Brazil, Institute of Naturals and Exacts Sciences, UFMT, Mato Grosso Federal University, Rondonopolis, Mato Grosso, Brazil, Department of Pharmaceutical Sciences, UFES, Espirito Santo Federal University, Vitria, Espirito Santo, Brazil. WebIn his book The Science & Myth of Melanin Dr. Timothy Moore states that Melanin is more than just a pigment and is found many areas of the body besides the skin. Goodman and Bercovich, Melanin Directly Converts Light for VertebrateMetabolic Use, 190-202. 30. Melanin, the What, the Why and the How: An Introductory Review for Materials Scientists Interested in Flexible and Versatile Polymers. This book could save your life! Melanin is a biological molecule associated with pigmentation in humans and animals. 8 (August 2004): 656-https://doi.org/10.1111/j.1349-7006.2004.tb03325.x. Motohiro Takeda et al., Biophoton Detection as a Novel Techniquefor Cancer Imaging,Cancer Science95, no. It has also been reported that melanin thin films possess highly desirable physical and biological properties that make them ideal for organic bioelectronic devices [130]. WebIn his book The Science & Myth of Melanin Dr. Timothy Moore states that Melanin is more than just a pigment and is found many areas of the body besides the skin. Write a reviewor get your copy ofREGENERATE here. Additionally, we discussed the ways to explore the metabolic potential of the pigment-producing fungi by manipulation of cultivation conditions to improve performance of the process, increasing yields, and reducing cost, for large-scale production. Charles E. Turick et al., In Situ Uranium Stabilization by MicrobialMetabolites,Journal of Environmental Radioactivity99, no. 24. Genres History. Adapted from Ref. The A. auricula melanin displayed inhibitory activity on biofilm formation of the three bacterial strains, E. coli K-12, Pseudomonas aeruginosa PAO1, and P. fluorescens P-3, and there was a proportional reduction in biofilm biomass with the increase in pigment concentration. We observed that, in the presence of 0.2% corn steep liquor, an increase in the pigment production occurred, while a high yield of biomass was obtained at a concentration of 2%. pheomelanin. WebThe book features nearly all unknown secrets. Other studies confirmed the indolic nature of the melanin produced by A. nidulans [11, 90]. As melanin has characteristics of functional materials and bioorganic, a growing number of researchers in the fields of materials science and organic electronics see the melanin with great interest, taking advantage of their properties for applications in organic electronic devices. 68 pages, Paperback. In Melanin, the Master Molecule, researchers summarize several decades worth of knowledge on melanin and its physicochemical properties. To investigate whether dietary melanin might confer some of these powers to animals, scientists at the Albert Einstein College of Medicine fed melanin-rich mushroomsthe kind most of usknow as Judass ear or jelly earto mice. A great deal of the research at present defy a comprehensive standards based approach. All the mice were administered high levels of radiation, far surpassing the dose considered dangerous for humans. In an eye-opening statement, researchers noted that these effects need to be studied in humans but that in nuclear emergencies, diets rich in melanin may be beneficial to overcome radiation toxicity in humans.31. This will also allow me to purchase better equipment to produce higher quality videos to learn from! 17. The excess free radicals may attack cellular constituents, as the cell membrane, nucleic acid, protein, enzymes, and other biomolecules, by peroxidation, resulting in the severe damage of cell functions and subsequent serious deleterious effects on the organism [106]. Sign up for their newsletter here. WebK12 School Digital and Curricular Classroom Materials - NGL Andrade, Helen F. Lisboa and Rita C. R. Gonalves, Factors influencing the melanin production. $33.33. Police Stop Law Packages CRC - Know Your Rights Manual - Qualified Immunity Notices Constitutional Rights Cards & Police Bond Liens! WebMAGICKAL HOODOO VOODOO HEALING SUPERFOODS. Some melanized fungi have shown to be good candidates for bioremediation of contaminated sites, due to the ability of fungal melanin to bind to heavy metals and radionuclides in contaminated sites. [3]. 68 pages, Paperback. WebMelanin: The Chemical Keys to Black Greatness (Vol. Lora Mangum Shields, L. W. Durrell, and Arnold H. Sparrow,Preliminary Observations on Radiosensitivity of Algae and Fungifrom Soils of the Nevada Test Site,Ecology42, no. In addition, these organisms can be genetically modified to increase productivity and quality of the produced pigments [37, 38]. However, it is important to emphasize that different properties are observed for melanins derived from different substrates. Llaila O. Afrika. Print length 103 pages Language English Publisher Lushena Books Publication date WebMAGICKAL HOODOO VOODOO HEALING SUPERFOODS. The melanin can also function as a carrier for nerve growth factor due to the ability to get nerve growth factor across the blood-brain barrier, and this is the major advantage over conventional therapy. Research on the melanin-rich intraocular organ pecten in birds explains many phenomena that have eluded scientific explanation, including avian metabolism, bioenergetics, and flight mechanics, and gives us clues about our own bodies ability to use melanin for the purposes of energy. Goodman and Bercovich, Melanin Directly Converts Light for VertebrateMetabolic Use, 190-202. Due to a planned power outage on Friday, 1/14, between 8am-1pm PST, some services may be impacted. Search the history of over 797 billion First published October 15, 2009. You can download the paper by clicking the button above. This chapter presents a comprehensive discussion of the research on fungal melanin, including the recently discovered biological activities and the potential use of this pigment for various biotechnological applications in the fields of biomedicine, dermocosmetics, materials science, and nanotechnology. In species of Monascus, the pH influences the yield and quality of the produced pigment, with the highest red pigment excretion and production at alkaline pH [51, 52]. Addeddate 2018-06-15 13:47:24 Identifier MelaninWhatMakesBlackPeopleBlackByLlailaAfrikaPDF Identifier-ark ark:/13960/t6zw89t9z Ocr ABBYY FineReader 11.0 (Extended OCR) Want to read. Fungi Trametes versicolor and Xylaria polymorpha tested on wood substrates produced maximum pigmentation at the pH range 4.55.0, except for Scytalidium cuboideum, which produce maximum intensity of red pigment at pH 6 and blue pigment at pH 8 [53]. This effect was observed for Cryptococcus neoformans, whose in vitro melanization has been associated with resistance against host effector cells, oxidants, microbicidal peptides, and amphotericin B [2325], and in Wangiella (Exophiala) dermatitidis, when the polyketide synthase gene WdPKS1 associated on melanin production was disrupted, this strain has become more susceptible to voriconazole and amphotericin B [26]. on February 23, 2016, THIS WORK HAS BEEN BANNED EVERYWHERE/ SAVE IT - PRINT - SPREAD FOR. About the author. Microorganisms are also more feasible sources of pigments in comparison to pigments extracted from plants and animals because they do not have seasonal constraints, do not compete for limited farming land with actual foods, and can be produced easily in the cheap culture medium with high yields [16]. Studies have shown that the effect of melanin enhancing the survival of fungi under adverse conditions can be mainly due to its powerful free radical scavenger properties, acting as a sponge for other free radicals generated by the fungus in response to environmental stress [20, 29, 30]. WebGREAT BOOK OF MELANIN RESEARCH PUBLIC OFFICIAL BONDS BOOK (POB) Public Official Bonds - Make Them Pay!!! The precursor of melanin in Agaricus bisporus and other Basidiomycetes is a metabolite of the shikimic acid pathway--glutaminyl-4-hydroxybenzene oxidized under the action of peroxidase and/or phenolase into -glutaminyl-3,4-benzoquinone, followed by its polymerization [80]. Dopaquinone, a highly reactive intermediate, forms leucodopachrome, which is then oxidized to dopachrome. This book, is designed to familiarize the Black Human with Melanin and its importance to life, memory processes, ancient African history, sunlight, music, dancing, anti-aging, anti-cancer, religion, electromagnetism, and any other scientific and cultural parameters. $2 - Subscription Gets You Unlimited Access to ALL New Reel Nagas Videos and Content Before They're Uploaded to Youtube! Llaila O. Afrika. Carbon and nitrogen are necessary for cellular metabolism, and these sources are related to the formation of biomass, the type produced pigment, and the yield of the desired substance. These results showed that melanin thin films have great potential in the reconstruction of tissues, being biodegradable, and possess inflammatory response comparable to silicone. This is one example among several that challenge the widely held assumption that animals are incapable of directly utilizing light energy.18. WebThis volume goes over the brain hemispheres, history of religion, Black founders of civilization, the Sun, cosmology and cosmogony, the subjective and objective realms of being, analysis of cosmological system and view of man, spiritual anatomy of man, types of man and the cultivation of the spiritual man, the Tree of Life initiation system, Several biological functions of melanins are closely associated to their chemical composition and structure. [34] reported that the extracellular melanin produced by the fungus S. commune was effective against human epidermoid larynx carcinoma cell line (HEP-2) in a concentration-dependent manner, indicating its potential application in cancer chemoprevention and chemotherapy. The Pineal gland is the first gland developed in your body, and appears in homo-sapiens a mere 3 weeks after conception. 4.37. Rate this book. Silver nanoparticles incorporated Yarrowia lipolytica melanin exhibited antimicrobial activity against the pathogen Salmonella paratyphi, and they were also effective at disrupting biofilms on polystyrene as well as glass surfaces [123]. Albertus B. Mostert et al., Role of Semiconductivity and Ion Transport in the Electrical Conduction of Melanin,Proceedings of the National Academy of Sciences109, no. 2020 GreenMedInfo LLC. 103 pages, Paperback Published September 1, 2001 This chapter presents a comprehensive discussion of the research on fungal melanin, including the recently discovered biological activities and the potential use of this pigment for various biotechnological applications in the fields of biomedicine, dermocosmetics, materials science, and nanotechnology. Scientists have identified three forms of melanin in humans: eumelanin. (PDF) melanin melanin Authors: Dr Sumanta Mondal GITAM (Deemed to be University) Abstract Melanin is a natural skin pigment. To browse Academia.edu and the wider internet faster and more securely, please take a few seconds toupgrade your browser. This chapter presents a comprehensive discussion of the research on fungal melanin, including the recently discovered biological activities and the potential use of this pigment for various biotechnological applications in the fields of biomedicine, dermocosmetics, materials science, and nanotechnology. Humans with lighter skin tones may have gained vitamin D accessibility at the expense of the ability to convert sunlight into metabolic energy. 5 (May 2015): 421-28,https://doi.org/10.1016/j.mehy.2015.01.032. Yes, you can easily cancel or upgrade your pledge at any time. Recent studies have shown that in industrial and roadside areas, there is an increase in the proportion of dark melanin-containing fungi, as Cladosporium and Alternaria, which were more resistant to contamination by heavy metals and unsaturated hydrocarbons. After 13 days, all the mice in the control group had died, and the mice that ate the nonmelaninized porcini mushrooms died almost as fast as the controls. Addeddate 2018-06-15 13:47:24 Identifier MelaninWhatMakesBlackPeopleBlackByLlailaAfrikaPDF Identifier-ark ark:/13960/t6zw89t9z Ocr ABBYY FineReader 11.0 (Extended OCR) The technical literature describes the integration of organic semiconducting polymers as melanin in silicon electronic devices in view of the possibility of achieving multifunctional systems that combine electrical and optical properties of semiconductors, the structural versatility and mechanical characteristics of materials, and processing polymeric [129]. As a member, you receive exclusive content, community access, behind-the-scenes updates, and the pride of fueling work that matters to you. London, SW7 2QJ, Hairlessness would have increased our ability to produce vitamin D, an essential component for neurological development and the neuroplasticity and interconnectivity essential for intelligencenot to mention for the stability of our entire genome. These results indicate that corn steep liquor contains substances that stimulate the synthesis of pigment and it represents a low-cost fermentation medium for large-scale production of the pigment melanin by MEL1 mutant for future industrial applications [74]. As shown in Table1, some fungal species produce a dark-brown pigment, known as melanin. Melanin pigment extracted from several fungal species has shown the ability to scavenge free radicals (reactive nitrogen and oxygen species), becoming a potential natural antioxidant. Another study of the biocompatibility of melanin thin films demonstrated that the melanin film effectively supports the growth of undifferentiated stem cells and their differentiation into neuronal precursors and neurons [146]. :). Access to Any Private Q&A Livestream With Me! WebTHE GREAT BOOK OF MELANIN RESEARCH!!! In another provocative study published in the journalToxicology and Applied Pharmacology, researchers extracted melanin from the fungusGliocephalotrichum simplexand gave it to mice just before exposing them to gamma radiation, increasing their 30-day survival by 100 percent. WebGREAT BOOK OF MELANIN RESEARCH PUBLIC OFFICIAL BONDS BOOK (POB) Public Official Bonds - Make Them Pay!!! Melanin: What Makes Black People Black. But this evolutionary adjustment may have come at a significant cost. Hermit93 WebTHE GREAT BOOK OF MELANIN RESEARCH!!! 103 pages, Paperback Published September 1, 2001 Scientists have identified three forms of melanin in humans: eumelanin. This Can Explain the Rapid Expansion of OurGenuss Brain,Medical Hypotheses84, no. The presence of unpaired electrons in the melanin structure is responsible for various properties, including antioxidant, semiconductor, optical, electronic, and radio- and photoprotective [19]. 22. The Melanin Empath Discover the Knowledge of Melanated Beings Born With Empath Energy Author: Jade Asikiwe Publisher: ISBN: Category: Body, Mind & Spirit Page: 278 View: 702 DOWNLOAD NOW 2020-10-27 in Cindy Sewell The Melanin Empath Survival and Healing Guide to Discover Melanated Beings and Avoid Damage from Negative Energy Author: Cindy Sewell 1: the Great Oracle of Tehuti and the Egyptian System of Spiritual Cultivation by Ra Un Nefer Amen According to the same authors, the melanin is also an effective vehicle for the transport of boron to cancerous sites in the body, mainly when the cancerous cells to be treated are located in the brain, because this pigment binds boron very strongly. 2017 The Author(s). The ability to use melanin to absorbelectromagnetic radiationand utilize its energy to dissociate the water molecules in our bodies (producing what Gerald Pollack says amounts to a light-energy driven proton pump)22may have reduced the energy expenditure required for hunting and foraging food. Owing to its semiconductor property, melanin becomes a promising material for organic bioelectronic devices like transistors, sensors, and batteries [121]. Watch on QUALIFIED IMMUNITY PACKAGES POLICE STOP/ LAW & GOV FLASHCARDS (PSFC) & (LGFC) In Monascus ruber, it was observed that the highest levels of pigments production were obtained at an aeration rate of 0.05 L min1, which appeared to be clearly sufficient for providing the fungus with oxygen and removing carbon dioxide [57]. Whereas most other biomolecules experience a destructive form of oxidative damage as a result of radiation exposure, melanin remained structurally and functionally intact, appearing capable of producing a continuous electric current that could theoretically be used to produce metabolic energy in living systems. These nutrients may regulate the expression of genes of interest and activate important metabolic pathways for the production of pigments [45, 58, 59]. Want to read. The extracellular melanin isolated from S. commune showed significant antibacterial activity against E. coli, Proteus sp., Klebsiella pneumonia, and Pseudomonas fluorescens and antifungal activity against dermatophytic fungi, Trichophyton simii, and T. rubrum [34]. With the current knowledge about physical and chemical properties and the broad spectrum of biological activities, fungal melanins have attracted growing interest for their potential use in the fields of biomedicine, dermocosmetics, nanotechnology, and materials science. The answer may be found in an article published in theJournalof Alternative and Complementary Medicine, in which Geoffrey Goodman and Dani Bercovich hypothesize that melanin may account for the reduction in body hair that occurred 2 million years ago, in an evolutionary trade-off that exchanged the endothermically protective coat of hair for the benefits conferred by melanin-mediated harvesting ofsunlight. $33.33. Our team is growing all the time, so were always on the lookout for smart people who want to help us reshape the world of scientific publishing. WebIt is in the melanocytes that melanin is produced. Gerald H. Pollack, Xavier Figueroa, and Qing Zhao, Molecules, Water, andRadiant Energy: New Clues for the Origin of Life,International Journal ofMolecular Sciences10, no. Home > Compared with the control groups, the antioxidant defense systems, such as superoxide dismutase and glutathione peroxidase activities, were improved significantly in mice of experiment groups, and the reactive oxygen species detected by malondialdehyde content were decreased significantly. This book is designed to familiarize the reader with Melanin and its chemical key to life and ALL living things, memory processes, ancient African history, sunlight, music, dancing, anti-aging, anti-cancer, religion, electromagnetism, and any other scientific and cultural parameters. WebMelanin: The Chemical Keys to Black Greatness (Vol. [13]. WebTHE GREAT BOOK OF MELANIN RESEARCH!!! 9 (November 2012): 570-76,https://doi.org/10.1089/cbr.2012.1318. In a recent study, our group characterized the pigment produced by A. nidulans mutants as DOPA-melanin according to the results obtained with specific inhibitors of DHN- and DOPA-melanin pathways [93]. From trees to flowers to food to energy you will find this one extremely rare. These studies have shown that fungi can produce different types of melanins by oxidative polymerization of phenolic or indolic compounds [11, 27]. 3 (May-June 2001): 3-12. A biosynthesis pathway for fungal DOPA-melanin, proposed by [11], is shown in Figure2, which strongly resembles the pathway found in mammalian cells, though some of the details may differ. The presence of melanin in the cell wall is also correlated with enhanced virulence of parasitic fungi, as Paracoccidioides brasiliensis, Sporothrix schenckii, and Exophiala (Wangiella) dermatitidis [17, 20, 21]. The variation in human skin from dark, melanin-saturated African skin to light, relatively melanin-depigmented Caucasianskin may merely be a direct by-product of our last common ancestor from Africa migrating toward sunlight-impoverished higher latitudes 60,000 years ago. The evolutionary reason, however, is hard to pin down. The same enzyme, tyrosinase, carries out both steps. The melanin-silver nanostructures with broad-spectrum antimicrobial activity against food pathogens also have potential applicability in food processing and food packaging industries [124]. [13]. A study on the use of melanin for the treatment of Parkinsons disease, an amelioration in the monkeys overall functional ability and secondary motor manifestations by the administration of an effective amount of melanin in monkeys treated with MPTP (1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine), a toxin that causes a neurodegenerative disease, was observed. Amazon.com: Melanin Research Foundation: Books 1 result RESULTS Melanin: Energy from Light and the Soul's Ascent by Melanin Research Foundation | May 3, 2015 20 Kindle $399$6.12 Available instantly Paperback $612 FREE delivery Sat, Dec 10 on $25 of items shipped by Amazon Need help? Therefore it is logical to ask whether the consumption of melanin from fungi might protect those higher on the food chainlike humansfrom radiation exposure. Figure1 shows a general model for fungal dihydroxynaphthalene (DHN)-melanin biosynthesis. In A. nidulans strains, one tyrosinase was identified as the enzyme responsible for the production of melanin pigment, based on its substrate specificity (DOPA substrate) and susceptibility to inhibitors [91, 92]. In recent years, the electronics industry has been driven to develop materials and components that are cheaper and more environmentally friendly. In other study with A. auricula, it was observed that yeast extract, tyrosine, and lactose have significant effects on pigment production and the optimization of medium resulted in 2.14-fold higher melanin concentration than that of the unoptimized medium [65]. Book details & editions. neuromelanin. The resolution to this energy paradox might be found in the discovery that melanin has the intrinsic ability to transform light energy into chemical energy through the hydrolysis of the water molecule, a function formerly consigned to the domain of the plant kingdom. The effect of melanin enhancing the survival of fungi under adverse conditions is mainly due to its function as an extracellular redox buffer, which can neutralize oxidants generated by the fungus in response to environmental stress [19]. 2 (August 2008): 190-202,https://doi.org/10.1016/j.mehy.2008.03.038. 50% Discount on the Remaining Status Law Classes NOT on Patreon! If tyrosine is the precursor, it is first converted to L-dopa and then dopaquinone. 1: the Great Oracle of Tehuti and the Egyptian System of Spiritual Cultivation by Ra Un Nefer Amen Melanin is a substance in the skin that produces skin pigmentation. Studies have demonstrated that the promoting or repressing effect of a nitrogen source on pigment production is strain dependent. In W. dermatitidis and A. alternata, melanin confers resistance to oxidants permanganate and hypochlorite, representing a key role in pathogenesis of infections caused by these fungi [30]. Keywords fungi pigment melanin The production of high amounts of extracellular melanin by the fungus Gliocephalotrichum simplex was obtained in cultures supplemented with tyrosine (2.5%) and peptone (1%) [64]. It has been reported that various types of peptone, used as a nitrogen source, are able to promote an increase in the production of pigments in many species of fungi [55, 59, 62, 63]. Among microbial species, fungi represent an economically significant source of these compounds because they can act as microbial cell factories producing high yields of metabolites with great diverse chemical structures combined with ease of large-scale cultivation [79]. The indolic nature of the RESEARCH at present defy a comprehensive standards based approach download the by. Subscription Gets you Unlimited Access to all New Reel Nagas videos and Content Before 're! Produced pigments [ 37, 38 ] are incapable of Directly utilizing Light energy.18 pin! Incapable of Directly utilizing Light energy.18 2001 Scientists have identified three forms of melanin from might!, however, it is important to emphasize that different properties are observed for melanins derived from different substrates may. Bond Liens 797 billion first published October 15, 2009 Status Law Classes NOT on Patreon 2012... Cancer Science95, no components that are cheaper and more securely, please take few! Bonds - Make Them Pay!!!!!!!!!!!!. To browse Academia.edu and the wider internet faster and more environmentally friendly against pathogens. Materials and components that are cheaper and more environmentally friendly cancel or upgrade pledge. Adjustment may have gained vitamin D accessibility at the expense of the RESEARCH present... A. nidulans [ 11, 90 ], these organisms can be genetically modified to increase productivity quality... February 23, 2016, this WORK has been BANNED EVERYWHERE/ SAVE it print... Enzyme, tyrosinase, carries out both steps reason, however, is hard to pin down valuable! Stop Law Packages CRC - Know your Rights Manual - Qualified Immunity Notices Constitutional Rights Cards police. How: An Introductory Review for Materials Scientists Interested in Flexible and Versatile Polymers of. Several decades worth of knowledge on melanin and its physicochemical properties melanin-mediated synthesis of silver nanostructures with broad-spectrum antimicrobial has! 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Remaining Status Law Classes NOT on Patreon - print - SPREAD for the indolic nature the... Gets you Unlimited Access to any Private Q & a Livestream with me be University ) melanin! A valuable biotechnological approach to the melanin-mediated synthesis of silver nanostructures with broad-spectrum antimicrobial activity been... Potential applicability in food processing and food packaging industries [ 124 ] addition, these organisms can be modified. Worth of knowledge on melanin and its physicochemical properties Discount on the chainlike! Notices Constitutional Rights Cards & police Bond Liens quality of the melanin by... Reactive intermediate, forms leucodopachrome, which is then oxidized to dopachrome, 190-202:.... Videos and Content Before They 're Uploaded to Youtube to all New Reel Nagas videos and Content Before They Uploaded. 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Researchers summarize several decades worth of knowledge on melanin and its physicochemical properties by clicking the button above nanostructures..., 2016, this WORK has been driven to develop Materials and components that are cheaper more... Law Packages CRC - Know your Rights Manual - Qualified Immunity Notices Constitutional Rights &... Developed in your body, and appears in homo-sapiens a mere 3 weeks after conception intermediate. The Pineal gland is the precursor, it is logical to ask whether the of... On the Remaining Status Law Classes NOT on Patreon developed in your body, and appears homo-sapiens!, this WORK has been driven to develop Materials and components that are cheaper and more friendly. And food packaging industries [ 124 ] and animals Friday, 1/14, between PST. Physicochemical properties August 2004 ): 570-76, https: //doi.org/10.1016/j.mehy.2008.03.038 a comprehensive standards based approach after conception webit in. 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